liposome相关论文
＜正＞Tumor-oriented nanocarrier drug delivery approaches with pH-sensitivity have been drawing considerable attentions over......
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Treatment of hepatoma with liposome-encapsulated adriamycin administered into hepatic artery of rats
AIM: To observe the therapeutic effects of liposome-encapsulated adriamycin (LADM) on hepatoma in comparison with adriam......
目的:通过meta分析方法评价紫杉醇脂质体联合顺铂在治疗晚期非小细胞肺癌患者方面的有效性和安全性。方法:计算机检索PubMed、CENT......
采用细胞色素c法研究了水杨酸铜分别在中性、正负电性脂质体中SOD样活性的变化情况.证明中性脂质体包裹的水杨酸铜的SOD样活性比水......
Objective:To investigate the effect of liposomemediated glial cell line-derived neurotrophic factor (GDNF) gene transfer......
AIM:To develop a hepatocyte targeting pH-sensitiveliposome for drug delivery based on active targetingtechnology mediat......
传统方法制备的脂质体存在粒径大、包封率低、分散不均匀、有机试剂残留等问题.动态高压微射流技术是一种新兴的脂质体制备技术,结......
阿尔茨海默病是老年人群中的一种常见病，严重影响患者生活质量，目前仍没有有效治疗手段，血脑屏障的存在则进一步限制了治疗药物药效的......
Macrophage depletion and Schwann cell transplantation reduce cyst size after rat contusive spinal co
Schwann cell transplantation is a promising therapy for the treatment of spinal cord injury (SCI) and is currently in cl......
Objective To evaluate the immune responses induced by experimental DNA construct encoding Toxoplasma gondii ( T.gondii )......
Self-assembly of Liposomes Loading Hinesol by Rapid Expansion from Supercritical to Surfactant Solut
本文通过对荣华二采区10...
为探究吕家坨井田地质构造格局,根据钻孔勘探资料,采用分形理论和趋势面分析方法,研究了井田7......
Cytotoxicity and Apoptotic Effect of Phytoceramide IV Containing Liposomes on Murine Mastocytoma Cel
为探究吕家坨井田地质构造格局,根据钻孔勘探资料,采用分形理论和趋势面分析方法,研究了井田7......
为探究吕家坨井田地质构造格局,根据钻孔勘探资料,采用分形理论和趋势面分析方法,研究了井田7......
目的 观察抗肝癌单链抗体经药剂学改造后对体外培养的肝癌细胞SMMC-7721的杀伤作用是否有所提高.方法 用IPTG诱导原核表达质粒PET3......
Ultrasound microbubbles combined with liposome-mediated pNogo-R shRNA delivery into neural stem cell
In the present study, ultrasound-mediated microbubble destruction (UMMD) alone and combined with liposome technology was......
Objective: The aim of our study was to investigate the biological effects of Bcl-XL antisense oligodeoxynucleotide (ASOD......
紫杉醇是目前全世界公认治疗肿瘤的有效药物，也是全球抗癌药物研究的热点。但是由于其毒副作用强、不溶于水等一些因素的影响，使其临......
目的以单纯胰岛素为对照,采用傅立叶红外转换光谱(Fourier Transform Infrared FTIR)研究包裹在脂质体内部胰岛素二级结构的变化.......
DNA疫苗是在基因治疗和转基因技术基础上产生的第三代疫苗,已成为当前疫苗研究领域的热点.因裸DNA疫苗直接接种存在诸多不足之处,......
Objective To evaluate the immune responses induced by experimental DNA construct encoding Toxoplasma gondii (T.gondii) s......
目的 研究COX-2反义RNA对肝癌细胞增殖抑制的作用及其机制,探讨肝癌治疗的新途径.方法 人工合成的COX-2反义RNA片段及无关对照空质......
目的 通过转铁蛋白靶向脂质体将外源性SDF-1基因跨血脑屏障转运至脑缺血大鼠脑内,观察SDF-1在脑缺血大鼠脑内的表达及对神经功能恢......
AIM: To study the anti-HBV effect of liposome-encapsulated matrine (Lip-M) in vitro and in vivo.METHODS: 2.2.15 cell lin......
Anti-hepatocarcinoma effects of 5-fluorouracil encapsulated by galactosylceramide liposormes in vivo
AIM: To study the anti-hepatocarcinoma effects of 5fluorouracil (5-Fu) encapsulated by galactosylceramide liposomes (5-F......
The bio- inspired strategy of triggered release of Ca2 +, Pi, F from prosomal compartments was used to induce rapid form......
目的 观察口服Ⅱ型胶原肽-霍乱毒素B亚单位-脂质体复合物对免疫耐受的诱导作用.方法 DBA/1小鼠分组,Ⅰ组:正常对照组,Ⅱ组:胶原诱......
hematological malignant tumors with CD19 high expression....
The cellular immunity of current influenza split vaccine is relatively low. It is necessary to develop a novel vaccine t......
目的:观察PP1脂质体滴眼对大鼠眼的急性毒性作用。方法:用10,60,400μmol·L~(-1)低、中、高3个不同浓度的PP1脂质体滴入SD大鼠单......
目的在前期制备出含羧基末端连接臂纳米脂质微泡的基础上,再在羧基末端连接抗体,制备出能够靶向HER2阳性乳腺癌细胞的纳米脂质微泡......
合成了具有隐形及靶向肿瘤组织功能的NGR多肽衍生物,并用基质辅助激光解析电离飞行时间质谱进行了表征。采用硫酸铵梯度法制备了用......
脂质体是脂质双分子层组成的囊泡结构,包裹的可溶性药物在体内可释放,具有无毒性和生物可降解性等优点.脂质体可将亚单位疫苗或核......
查阅国内外文献，采用整理归纳、引用和分析的方法，概述了鼻黏膜免疫载体材料脂质体、免疫刺激复合物和壳聚糖的生物学特性及其在气溶......
目的 在利用正交试验进行脂质体的处方筛选时,采用新的统计方法对试验得到的数据进行分析.方法 选择粒径、zeta电位、包封率和物理......
采用薄膜-超声分散法制备蛇床子素脂质体,以包封率为评价指标,采用单因素考察和正交试验优化蛇床子素脂质体的处方和工艺条件。所......
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The standard rabies vaccines recommended by WHO include Essen regimen, the Thai Red Cross two-site ID regimen and the ei......
Preparation and Targeting Evaluation of Recombined Intrakine Plasmid pEGFP/SDF-1/KDE/Folate-Liposome
Objective: To prepare folate liposome complexes of recombinant plasmid pEGFP/SDF-1/KDEL with contained intrakine SDF-1/K......
Synthesis Hexadecyl 3-{4-[2-Hydroxy-3(isopropylamino)propoxy]phenyl}propionate as Potential Ligand f
Novel hexadecyl 3- { 4-[2-hydroxy-3(isopropylamino)propoxy]phenyl }propionate (HPP)was synthesized and its effect on del......
基因治疗是将遗传信息通过一定方式导入人体特定细胞,指导合成特定蛋白质,从而治疗疾病的生物技术.良好的基因载体对基因有效载入......
The synthesis of a new type of X-ray-sensitive compound “di-(1-hydroxylundecyl)diselenide” and its application in the ......
目的优化茶多酚(TP)脂质体温敏凝胶的制备工艺。方法采用薄膜超声分散法制备TP脂质体,并以包封率为考察指标,通过单因素试验和正交......
目的:黑色素瘤,又称恶性黑色素瘤,是由于黑色素细胞发生病变造成的一种致命性的恶性肿瘤。黑色素瘤常见于皮肤,亦见于黏膜、眼脉络......
通过自组装技术将葡萄糖氧化酶脂质体与纳米石墨烯共修饰于玻碳电极表面,制备出新型葡萄糖氧化酶电化学生物传感器,并利用其构建重......
目的制备并评价马来酸桂哌齐特脂质体(CM-Lip)。方法采用逆向蒸发法制备CM-Lip,以包封率为考察指标,结合鱼骨图分析法和Plackett-B......
目的:为了得到苍耳子油脂质体的最佳制备工艺。方法:以卵磷脂和胆固醇为膜材,采用薄膜分散水化法制备脂质体,利用游离药物与含药脂......
目的观察脂质体载体pcDNA3-TGF-β1基因治疗对同种心脏移植物存活的影响.方法大量扩增pcDNA3-TGF-β1,制备脂质体-靶基因混合物及......
目的：建立高效液相色谱法（high performance liquid chromatography，HPLC）测定奥扎格雷钠脂质体包封率的检测技术。方法采用HPLC，以C18......
